MECHANISMS OF ENDOTOXIN TOLERANCE IN RELATION TO CARBOHYDRATE METABOLISM
نویسندگان
چکیده
منابع مشابه
Mechanisms of Endotoxin Tolerance
Healthy male volunteers were rendered tolerant to the pyrogenic and toxic activities of bacterial endotoxin by daily intravenous injections. Five subjects were given 0.5 microg Salmonella typhosa endotoxin for 7 days; four subjects were given Pseudomonas endotoxin, increasing over a period of 30 days from 25 to 250 microg. Reticuloendothelial system (RES) phagocytic activity was assessed by ser...
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The phenomenon of endotoxin tolerance has been widely investigated, but to date, the molecular mechanisms of endotoxin tolerance remain to be resolved clearly. The discovery of the Toll-like receptor (TLR) family as the major receptors for lipopolysaccharide (LPS) and other bacterial products has prompted a resurgence of interest in endotoxin tolerance mechanisms. Changes of cell surface molecu...
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ژورنال
عنوان ژورنال: The Japanese Journal of Physiology
سال: 1963
ISSN: 1881-1396,0021-521X
DOI: 10.2170/jjphysiol.13.486